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Dr. Victor Ling Professor, Department of Medical Biophysics University of Toronto Head, Division of Molecular and Structural Biology The Ontario Cancer Institute Toronto, Canada M4X 1K9 |
Deciphering the mechanisms why cancer cells become resistant to chemotherapy is the main theme of Victor Ling's work. He discovered and analyzed a membrane protein (P-Glycoprotein) that pumps a variety of anticancer drugs out of malignant cells before these drugs have a chance to act. Based on V. Ling's studies, clinical trials are underway which use immune suppressive drugs that clog the membrane pumps allowing previously resistant cells to become sensitive again.
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Freitag, 16. Dezember 2005 |